Breast cancer, the most common cancer in women worldwide, may one day be treated using the venom of the European honeybee.
Dr Ciara Duffy from Western Australia’s Harry Perkins Institute of Medical Research has found that venom from honeybees can rapidly kill aggressive and hard-to-treat breast cancer cells. NCRIS-enabled facilities at the Centre for Microscopy, Characterization and Analysis (CMCA), UWA, were integral to the research, published recently in the journal Nature Precision Oncology.Read More
Proper vascular development of the human placenta is crucial for meeting the metabolic needs of the developing fetus during pregnancy. Maternal environmental stressors such as malnutrition disrupt the elaboration of the feto-placental vasculature that, in turn, impacts on placental function and results in reduced fetal growth. The ramifications of this are not only on short-term foetal health but also on long-term health outcomes. Indeed, distortion in placental shape and size strongly associate with later adult health outcomes such as cardiovascular disease, obesity and cancer.Read More
Re-regeneration to reduce adverse effects associated with tail loss
Caudal autotomy, the ability to drop and regenerate a portion of the tail, is a widely used anti-predation strategy in many lizard species. Intra-vertebral autotomy planes within a series of the lizard’s caudal vertebrae allow individuals to autotomise a portion of their tail to escape a threat, such as a predator’s grasp. Once autotomised, the tail regenerates with a rigid cartilage rod in place of the original bony vertebrae. Although an effective anti-predation strategy, it has both short and long-term costs to the individual associated with physical tail loss, as well as the energy required for regeneration. Additionally, a regenerated tail lacks autotomy planes, where subsequent autotomy events having to at a more proximal position at a caudal vertebra with an intact autotomy plane.Read More
The Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS) exists to enable national-scale research facilities, thereby facilitating Australian researchers to address critical national and global challenges effectively and efficiently. NCRIS projects provide equipment, resources, analysis tools and, importantly, expertise.Read More