Only two in ten people diagnosed with brain cancer will survive for at least five years, a figure that has barely improved in the last 30 years. Due to the blood-brain barrier and the risk of damaging normal brain tissue, brain cancer treatments are complex and multidisciplinary. Despite advances in surgical techniques, radiotherapy and chemotherapeutics, brain tumours remain challenging to treat. Hence, image-guided microbeam radiation therapy (MRT) with nanoparticle enhancement is being investigated for the treatment of brain cancer in animal models.

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