University of Melbourne

About

The University of Melbourne (UoM) NIF Node empowers groundbreaking research in biomedical imaging, providing access to world-class advanced human and frontier imaging technologies, and cutting-edge radiopharmaceutical facilities across two clinical sites and the UoM main Parkville campus.

The UoM node supports radiochemistry facilities at Austin Health (AH) and the Peter MacCallum Cancer Centre (PMCC), two Departments with internationally recognised reputation in basic, translational and clinical research into PET imaging and theranostics in neuroscience, oncology and metabolic diseases. AH and PMCC have established radiochemistry, cyclotron, preclinical and clinical infrastructure for developing, validating and translating novel radiopharmaceuticals into the clinic.

At the PMCC, the Australian Cancer Research Foundation’s Centre for Advanced Imaging-Guided Cancer Therapeutics spearheaded the 2025 installation of a world-first next-generation GE Healthcare OMNI 128 Total Body PET/CT, representing a major advance in human scanning, enabling accelerated development of cancer imaging and therapeutics to support prevention, early detection and advanced cancer research programs. The platform enables ultra-fast total body human molecular scanning allowing new applications including dynamic pharmacodynamic imaging for validation of novel tumour-targeted radiotracers, immune system imaging, cell tracking and paediatric applications.

The Melbourne Brain Centre Imaging Unit (MBCIU) on the UoM Parkville campus is an innovative imaging facility dedicated to advancing medical imaging research. Equipped with state-of-the-art technology including a 7T MRI scanner, a PET/CT camera and Australia’s first OPM-MEG system, the MBCIU supports collaboration between researchers and clinicians exploring a wide range of conditions, from neurological disorders like multiple sclerosis and Alzheimer’s disease to cognitive neuroscience research studies. The MBCIU’s expertise spans anatomical, functional and molecular imaging, providing high-resolution, non-invasive insights into the brain and other body systems.

The UoM node hosts the partnership between NIF and the ARC Centre of Excellence in Plants for Space, developing plant-soil systems imaging capabilities, enabling researchers to gain dynamic insight into the interactions between plants and their soil environments, and fostering advancements in agriculture, environmental sustainability, and ecosystem health.

Locations

Melbourne Brain Centre Imaging Unit (MBCIU)

Kenneth Myer Building
30 Royal Parade
Parkville VIC 3052

Austin Hospital

145 Studley Road
Heidelberg VIC 3084

Peter MacCallum Cancer Centre

305 Grattan Street
Melbourne VIC 3052

Publications

Effect of [68Ga]Ga-PSMA-11 PET-CT in the diagnosis of prostate cancer in men with equivocal or clinically high-risk non-suspicious findings on multiparametric MRI (PRIMARY2): a multicentre, non-inferiority, phase 3, randomised controlled trial

James P Buteau MD, Daniel Moon MBBS, Michael T Fahey PhD, Matthew J Roberts PhD, Narjess Ayati MD, Nathan Papa PhD, Prof Declan G Murphy MBBCh, Prof Veeru Kasivisvanathan PhD, Prof Haryana M Dhillon PhD, Yang T Du MBBS, Philip Dundee FRACS, Jessica Foudoulis MHIM, David Hennes MD, Anthony C Hutton FRACS, Jordan Idiare MBBS, Greg Jack FRACS, Sheshang Kamath FRACS, Sophie N Lee PhD, Su-Faye Lee FRANZC, Prof Sze Ting Lee PhD, Alex Zheng

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First Images on a Next-Generation Extended–Field-of-View Digital Bismuth Germanium Oxide Total-Body PET/CT

Michael S. Hofman, Alicia Corlett, Cameron Pain, Price Jackson, Ramin Alipour, Grace Kong, Aaron J.N. Wong, James Buteau, Tim Akhurst, Dulash Fernando, Shankar Siva and Declan G. Murphy

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A comprehensive framework for automated segmentation of perivascular spaces in brain MRI with the nnU-Net

William Pham, Alexander Jarema, Donggyu Rim, Zhibin Chen, Mohamed Khlif, Vaughan Macefield, Luke Henderson & Amy Brodtmann

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Epileptogenic lesions in the Australian epilepsy project: A harmonized 3-T magnetic resonance imaging protocol and its diagnostic yield

David N. Vaughan, David F. Abbott, Amanda Anderson, Greg Fitt, Suyi Ooi, Heath Pardoe, Donna Parker, Yuliya Perchyonok, Eric Pierre, Chris Kokkinos, Robert E. Smith, Michael Stewart, Bahman Tahayori, Chris Tailby, Graeme D. Jackson, the Australian Epilepsy Project Investigators

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