Projects

New diagnostic strategies to determine cardiovascular risk

Despite significant advances in diagnostic and therapeutic technologies, cardiovascular disease (CVD) remains the global leading cause of death, accounting for 17.3 million deaths per year, and is expected to grow to more than 23.6 million by 2030. Currently, the prevention of MI and stroke is limited due to the lack of sensitive imaging methods. Those…

Read more 10:37 am 5 Jun 2018

The uncovered toxins in Fang Blenny fish venom could pave the way for new medications

The UQ Node of the National Imaging facility has recently helped a scientific breakthrough in the field of venom research. The 3D image of a fang blenny reef fish was produced at the Centre for Advanced Imaging using the Siemens micro CT scanner. It was part of an international study led by Professor Bryan Fry…

Read more 10:17 am 5 Jun 2018

Bringing extinct Australia fauna back to life

What do long extinct pig-footed bandicoots, anatomical education and 3D printing have in common? Justin Adams and Paul McMenamin of the Centre for Human Anatomy Education at the Monash Department of Anatomy and Developmental Biology are using imaging data generated by the Monash NIF node fellows and the radiography team at Monash Biomedical Imaging. Their…

Read more 3:58 pm 4 Jun 2018

National network of trusted data repositories establish standard for the future

Imaging equipment such as MRI, PET and CT scanners are capable of producing vast amounts of valuable research data. In order to maximise research outcomes, data must be stored securely, have its quality verified, and should be accessible to the wider research community. Informatics fellows from around Australia have combined their expertise to build a…

Read more 12:22 pm 8 Jan 2018

Imaging Data, a Treasured Asset

Micro-CT imaging data collected at CAI by National Imaging Facility (NIF) Fellow, Dr Karine Mardon, has been transformed into an interactive display as part of the 200 treasures exhibition at the Australian Museum’s newly restored Long Gallery (now Westpac Gallery). The data has been reconstructed to create a multimedia, interactive exhibit where visitors can see…

Read more 12:15 pm 8 Jan 2018

PhysIO – An open-source toolbox to model physiological noise in fMRI

In a collaborative project led by Lars Kasper from the Translational Neuromodeling Unit (TNU) and the Institute for Biomedical Engineering at the University of Zurich and ETH Zurich together with National Imaging Facility (NIF) Fellow Steffen Bollmann from the Centre for Advanced Imaging (CAI), The University of Queensland node, a new open source toolbox for…

Read more 9:43 am 10 May 2017

Novel Tractography to Detect Mild Traumatic Brain Injury

A mild traumatic brain injury (mTBI), often referred to as a concussion, rarely has lasting effects and is often presumed to cause only transient disturbances to brain function. However, repeated mTBIs, particularly those occurring in the sports and military settings, have been associated with cumulative and chronic neurological impairments, and the development of neurodegenerative diseases…

Read more 10:22 am 4 May 2017

Imaging adds a new dimension into student learning

Life presents itself in an intriguing array of three-dimensional structures. Through hands-on examination of specimens, students are presented with a highly valuable resource that aids their understanding of the diversity and complexity of taxa. However, the fragility, rarity and cost restricts the number and diversity of physical specimens that educators can provide to their classes….

Read more 11:41 am 7 Nov 2016

Imaging for a better understanding of Anorexia Nervosa

Anorexia Nervosa (AN) is a serious psychiatric condition characterised by significantly low body weight and a fear of weight gain. A disturbance in the experience of one’s own body weight or shape is a core feature of the illness, which has a mortality rate among the highest of any mental illness. Thus, it is critical to gain a better understanding of the neurobiological basis of…

Read more 12:33 pm 4 Oct 2016

Visualisation and Characterisation of Feto-placental Vasculature

Proper vascular development of the human placenta is crucial for meeting the metabolic needs of the developing fetus during pregnancy. Maternal environmental stressors such as malnutrition disrupt the elaboration of the feto-placental vasculature that in turn impacts on placental function and results in reduced fetal growth. The ramifications of this are not only on short-term…

Read more 1:17 pm 26 Aug 2016

Grape split imaging to examine physical changes before and after splitting using diffusion magnetic resonance

Berry split is a condition in which the grape epidermis splits which often occurs during periods of high rainfall and is a significant cause of grape crop loss. In damp conditions there is increased uptake of water via osmosis and decreased water loss from transpiration. The pre-dawn turgor pressure of table grape cultivars lies in…

Read more 3:02 pm 8 Jun 2016

Abnormal brain areas common to the focal epilepsies

A group of scientists at The Florey Institute may soon be able to diagnose a common form of epilepsy after a simple 10-­minute brain scan. The result? Patients will commence immediate treatment and minimize the risk of further damage caused by seizures. New research published in Brain Connectivity shows that people with focal epilepsy seemingly…

Read more 10:33 am 3 Jun 2016

Simultaneous scanning of two mice in a small-animal PET scanner

In preclinical Positron Emission Tomography (PET) imaging, several research groups have recently proposed different experimental set ups allowing multiple animals to be simultaneously imaged in a scanner in order to reduce the costs and increase the throughput. Simultaneous scanning of several animals also ensures injections with the same specific activity, which may be otherwise subject…

Read more 9:44 am 25 May 2016

Enhanced MRI of Preclinical Prostate Cancer

  MRI is a useful imaging tool in prostate cancer management. It provides excellent soft tissue contrast and multidimensional information, does not involve exposure to ionizing radiation, and is non-invasive. However, like other imaging modalities such as computed tomography (CT), transurethral ultrasound (TRUS) and nuclear imaging, MRI cannot adequately detect small tumors. The ability to…

Read more 11:10 am 4 Feb 2016

Global BioImaging Project

  AMMRF and NIF announce their inclusion in EU Horizon 2020-funded Global BioImaging (GBI) project that commences today. The grant to Euro-BioImaging is built on their existing collaboration with two NCRIS-supported projects, the Australian Microscopy & Microanalysis Research Facility (AMMRF) and the National Imaging Facility (NIF) and with India-BioImaging, around imaging infrastructure. Euro‐BioImaging is a large‐scale…

Read more 3:42 am 1 Dec 2015

Industry engagement: Contrast free MR angiography

Angiography is a common medical imaging technique that is used to visualise organs and blood vessels of the body. In order to obtain best images, Gadolinium-based contrast agent is the most commonly used chemical to enhance the visualisation of the vessels.

Read more 5:55 am 8 Jan 2015

Multi-Organ Simultaneous Dynamic Gd-MRI and FDG PET in the Mouse

Targeted or “smart” biological compounds are a rapidly expanding field for the next generation of drugs for disease treatment and enhancing plant and animal production. Traditional methods, such as MRI and PET, measure the uptake of an agent with a single label via a single imaging modality,

Read more 5:54 am 8 Jan 2015

Pre-clinical MRI: Insights into Canavan disease

Canavan disease is a metabolic disorder of the cen tral nervous system (CNS) caused by mutations in the aspartoacylase (ASPA) gene.

Read more 1:17 pm 10 Sep 2014

Understanding Alzheimer’s - A collaborative approach

Imaging research is increasingly a collaborative endeav our. Across the world, there are a number of large medi cal research consortia

Read more 1:17 pm 10 Sep 2014

Multi-modality Research Imaging Informatics Repository

Biomedical imaging research increasingly involves acquir ing, managing and processing large amounts of distributed imaging data. A bit more text as an example here.

Read more 1:16 pm 10 Sep 2014

Brain Structure and Volume Variation of Australian Agamid Lizards under Constrating Natural and Sexual Selection

Australian National University PhD student Daniel Hoops is accessing the University of Western Sydney (UWS) NIF node to investigate how sociality,

Read more 1:15 pm 10 Sep 2014

Tracking of Dendritic Cells using Fluorine-19 label by MRI in mouse model

Biomedical science prepares for another revolution with immunotherapies being widely regarded as the next pillar of medicine

Read more 1:14 pm 10 Sep 2014

Assessing MRI Biomarkers in a Rat Model of Concussion

Concussion, a subset of mild traumatic brain injury (mTBI), is gaining prominence as a serious medical and societal issue worldwide

Read more 8:19 am 29 Aug 2014

The Role of Carotid Rete Variability in Sheep

Professor Stuart Bunt from the School of Anatomy, Physiol ogy and Human Biology at The University

Read more 8:10 am 29 Aug 2014

Characterisation of the cortical shell and trabecular architecture of the lateral masses of the human cervical spine

Professor Brett Kirk from the School of Civil and Mechanical Engineering at Curtin University

Read more 8:05 am 29 Aug 2014